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FrenchGlory ® isotonic OPC 3 antioxidant products are dietary and nutritional supplements, not intended to diagnose, treat, care or prevent any diseases.


Cuevas VM, Calzado YR, Guerra YP, Yera AO, Despaigne SJ, Ferreiro RM, Quintana DC.
Effects of grape seed extract, vitamin C, and vitamin e on ethanol- and aspirin-induced ulcers.
Adv Pharmacol Sci. 2011:740687. Epub 2011 Nov 20.


1. Pfleger CM, Wang J, et al. Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy. Int J Alzheimers Dis. 2010 Aug 24;2010.

2. Wang YH, Yang XL, et al. Effects of proanthocyanidins from grape seed on treatment of recurrent ulcerative colitis in rats. Can J Physiol Pharmacol. 2010 Sep;88(9):888-98.

3. Park MK, Park JS, et al. Grape seed proanthocyanidin extract (GSPE) differentially regulates Foxp3(+) regulatory and IL-17(+) pathogenic T cell in autoimmune arthritis. Immunol Lett. 2011 Mar 30;135(1-2):50-8.

4. Yoo DY, Kim W, et al. Grape seed extract enhances neurogenesis in the hippocampal dentate gyrus in C57BL/6 mice. Phytother Res. 2010 Oct 29. doi: 10.1002/ptr.3319.

5. El-Beshbishy HA, Mohamadin AM, et al. Amelioration of tamoxifen-induced liver injury in rats by grape seed extract, black seed extract and curcumin. Indian J Exp Biol. 2010 Mar;48(3):280-8.

6. Dos Santos PH, Karol S, Bedran-Russo AK. Nanomechanical properties of biochemically modified dentin bonded interfaces. J Oral Rehabil. 2010 Nov 9. doi: 10.1111/j.1365-2842.2010.02175.x

7. Ling LT, Palanisamy UD, Cheng HM. Prooxidant/antioxidant ratio (ProAntidex) as a better index of net free radical scavenging potential. Molecules. 2010 Nov 3;15(11):7884-92.

8. Zhang Y, Shi H, et al. Antithrombotic effect of grape seed proanthocyanidins extract in a rat model of deep vein thrombosis. J Vasc Surg. 2010 Nov 20.

9. Hanausek M, Spears E, et al. Inhibition of murine skin carcinogenesis by freeze-dried grape powder and other grape-derived major antioxidants. Nutr Cancer. 2011 Jan;63(1):28-38.

10. Chao CL, Chang NC, et al. Grape seed extract ameliorates tumor necrosis factor-α-induced inflammatory status of human umbilical vein endothelial cells. Eur J Nutr. 2010 Nov 28.

11. Cady RJ, Hirst JJ, Durham PL. Dietary grape seed polyphenols repress neuron and glia activation in trigeminal ganglion and trigeminal nucleus caudalis. Mol Pain. 2010 Dec 10;6:91.

12. Bedran-Russo AK, Castellan CS,et al. Characterization of biomodified dentin matrices for potential preventive and reparative therapies. Acta Biomater. 2010 Dec 16.

13. Kulkarni S, Desantos FA, et al. Effect of grape seed extract on oxidative, color and sensory stability of a pre-cooked, frozen, re-heated beef sausage model system. Meat Sci. 2010 Dec 10.

14. Ksiezak-Reding H, Ho L, et al. Ultrastructural alterations of Alzheimer's disease paired helical filaments by grape seed-derived polyphenols. Neurobiol Aging. 2010 Dec 31.

15. Charradi K, Sebai H, et al. Grape Seed Extract Alleviates High-Fat Diet-Induced Obesity and Heart Dysfunction by Preventing Cardiac Siderosis. Cardiovasc Toxicol. 2011 Jan 14.

16. Park SY, Lee YH, et al. Grape seed extract regulates androgen receptor-mediated transcription in prostate cancer cells through potent anti-histone acetyltransferase activity. J Med Food. 2011 Jan-Feb;14(1-2):9-16.

17. Colindres P, Susan Brewer M. et al. Oxidative stability of cooked, frozen, reheated beef patties: effect of antioxidants. J Sci Food Agric. 2011 Jan 19. doi: 10.1002/jsfa.4274.

18. Jia Z, Song Z, et al. Grape seed proanthocyanidin extract protects human lens epithelial cells from oxidative stress via reducing NF-кB and MAPK protein expression. Mol Vis. 2011 Jan 20;17:210-7.

19. Kaur M, Tyagi A, et al. Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and post-transcriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells. Mol Carcinog. 2011 Jan 25. doi: 10.1002/mc.20739.

† These statements have not been evaluated by the US Food & Drug Administration.

FrenchGlory ® isotonic OPC 3 antioxidants are nutritional supplements solely for nutritional deficiency-caused health problems and not intended to diagnose, treat, care for or prevent any general diseases.
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Grape Seed Extract Scientific Research Update at OPC 123