Summary: Declaration of raw OPC-3 ingredients to OPC consumers is a new standard of isotonic OPC products, only from FrenchGlory ® Isotonic OPC Antioxidants, Inc. Don’t buy any OPC products without seeing the detailed specifications for all OPC 3 ingredients on sellers’ web sites. Extraction of OPC ingredients demands advanced refining technologies. Low grade OPC ingredients contain much polymeric proanthocyanidins and are potentially harmful to your immune system as polymeric proanthocyanidins prevent mineral absorption as strong metal chelators. OPC quality is the key.
FrenchGlory ® OPC antioxidants contain the following 2 or 3 OPC extracts:
1. Vitaflavan ® French grape seed extract OPC: polyphenols > 96%
Maker: DRT Nutraceutics in France.
Vitaflavan ® is a registered trademark of DRT Nutraceutics in France.
Vitaflavan® OPC is a fine OPC powder as a French grape seed extract, grown in the South West region. OPC biological activity is linked to the type of procyanidin (OPC). Not all procyanidins have a biological effect. The OPCs’ intestinal absorption and thus their biological activity are based on the OPC molecular weight, the high weight OPC molecules being unabsorbed. Vitaflavan® OPC presents an optimal OPC composition in oligomeric procyanidins, which guarantees bioavailability and effectiveness of the OPC extract. Several OPC grape seed extracts are now available in the market. However, only Vitaflavan® OPC grape seed extract has a high OPC content in short oligomers of catechin and epicatechin, and is characterized by an absence of high molecular weight tannins larger than pentamers. Vitaflavan® GSE is a bulk OPC raw ingredient from grapeseeds, the world-best health ingredient to fight antioxidant deficiency-induced health problems due to imbalanced diet.
TOTAL POLYPHENOL CONTENT > 96%
MONOMERS: 22%
DIMERS: 19%
TRIMERS UP TO PENTAMERS: 56%
PROCYANIDIN CONTENT (GPC): > 75%
PROCYANIDIN CONTENT (PORTER): > 68%
ANTIOXYDANT ACTIVITY
ORAC VALUE (μMOL TEQ/G): 19000.
Vitaflavan® OPC extract has been tested in vitro and in vivo by different methods and laboratories, standing out as the grape seed extract OPC of high purity in the world by the most extensively characterizations. Orac value of Vitaflavan® grape seed extract OPC extract is about 19,000 μmol TE/g*.
Vitaflavan ® GSE has been investigated in depth for health benefits. For example, scientific research data indicate that it may have the benefit in helping weight management for people of imbalanced diet. Vitaflavan® OPC may play a role in weight management by reducing the energy intake to overweight dietary unrestrained subjects.† Biological studies indicate that Vitaflavan® grape seed extract OPC may decrease the adipocytes differentiation and to activate the lipolyse with short and long term via actors such as to cAMP, PKA, HSL, G 3PDH, PPAR.†
and Treat Your Body with the World-best ® Antioxidants!
It Is Your Body! It Is Your Choice!
2. Oligopin® French maritime pine bark extract OPC: polyphenols > 96%
Maker: DRT Nutraceutics in France.
Oligopin ® is a registered trademark of DRT Nutraceutics in France.
Oligopin® OPC is a fine OPC powder as a French maritime pine bark extract, grown in the South West region. Oligopin® pine bark extract presents an optimal OPC composition in oligomeric procyanidins, which guarantees bioavailability and effectiveness of the OPC extract. Several OPC pine bark extracts are now available in the market. However, only Oligopin® OPC has a high OPC content in short oligomers of catechin and epicatechin, and is characterized by an absence of high molecular weight tannins larger than pentamers. Oligopin ® OPC has high antioxidant activity with ORAC value of about 15,000 μmol TE / g*. Oligopin ® PBE is a raw bulk OPC ingredient from pinebark.
TOTAL POLYPHENOL CONTENT > 96%
MONOMERS: 28%
DIMERS: > 15%
TRIMERS UP TO PENTAMERS: 50%
PROCYANIDIN CONTENT (GPC): > 67%
PROCYANIDIN CONTENT (PORTER): 70%
ANTIOXYDANT ACTIVITY
ORAC VALUE (μMOL TEQ/G): 15000.
Oligopin ® OPC pine bark extract has been tested in vitro and in vivo by different methods and laboratories, standing out as pine bark OPC of the highest purity, and as one of the most precious French maritime pine bark extracts by the most extensively characterizations, on a basis of solid scientific data.
The Oligopin® pine bark extract OPC health benefits include those for cardiovascular health, veins health and circulation enhancer, anti-ageing - skin elasticity. It is a good supplement for pigmentation problems, etc. †
Oligopin® OPC pine bark extract demonstrates in vitro a strong affinity for the LDL particles. This OPC affinity conjugated with its anti-free radical properties suggests a potential OPC activity against LDL oxidation, which is the key of the atherosclerosis risk component. In an in vivo OPC experiment conducted during 8 weeks at the GBSA in Montpellier (France) in 2002, accumulation of oxidized lipids on the surface of arteries of syrian hamsters, fed with an hypercholesterolemic diet, was significantly reduced with a 15 mg/kg Oligopin® OPC supplementation. In parallel, a supplementation with 82 mg/kg of high polymeric tannins is much less efficient in the same conditions. † The solid scientific data indicate that OPC pine bark extrac is an excellent supplement to fight nutritional deficiency, namely antioxidant deficiency, and related health problems.
and Treat Your Body with the World-best ® Antioxidants!
It Is Your Body! It Is Your Choice!
3. ExGrape ® red wine extract OPC: polyphenols > 92%
Maker: GROUPE GRAP'SUD in France.
ExGrape ® is a registered trademark of GROUPE GRAP'SUD in France.
ExGrape ® red wine extract OPC is a unique total profile of red wine polyphenols, and affects on aortic lipid deposition shown by scientific studies.† ExGrape ® Total OPC is a strong antioxidant with ORAC value (over 17 000), equivalent or superior to the best grape OPCs in the world, and has greater antioxidant activity than any other red wine extract OPCs.
and Treat Your Body with the World-best ® Antioxidants!
It Is Your Body! It Is Your Choice!
The OPC specifications of 3 extracts in FrenchGlory ® OPC products: Oligopin ® pine bark extract, Vitaflavan ® grape seed extract and red wine exGrape ® extract are available in the 3 manufacturers’ web sites:
References
WARNING: The OPC scientific studies are cited here for information only, and do not mean that OPC can be used to treat/prevent diseases according to the US FDA regulations on diestary supplements.
Examples of scientific research conducted using Vitaflavan ® grape seed extract OPC:
1. A Ardevol, C Blode, MJ Salvado and L Arola; Changes in lipolysis and hormone-sensitive lipase expression caused by procyanidins in 3T3-L1 adipocytes. International Journal of Obesity (2000) 24, 319-324.
2. M Pinent, MC Blade, MJ Salvado, et al. Grape seed derived procyanidins interfere with adipogenesis of 3T3-L1 cells at the onset of differentiation. International Journal of Obesity (2005) 1-8.
3. M Pinent, MC Blade, MJ Salvado, et al. Intracellular Mediators of Procyanidin-induced Lipolysis in 3T3-L1 Adipocytes. Journal of Agricultural and Food Chemistry (2005) 53, 262-286.
A recent example of scientific research conducted using Oligopin ® French maritime pine bark extract OPC:
4. Elise Dargelosa, Cédric Bruléa, Pascal Stuelsatza, et al. Up-regulation of calcium-dependent proteolysis in human myoblasts under acute oxidative stress; Experimental Cell Research (2010) 316, 115-125.
References related to red wine ExGrape ® OPC extract:
5. AUGER Cyril et al. Red wine phenolic compounds reduce plasma lipids and apolipoproteinB and prevent early aortic atherosclerosisin hypercholesterolemicgolden Syrian hamsters. American Society for Nutritional Sciences (2002) 1207-12132.
6. ZERN Tosca L. et al. Grape polyphenols decrease plasma triglyceridesand cholesterol accumulation in the aorta of ovariectomizedGuinea pigs. American Society for Nutritional Sciences (2003) p2268-2272.
7. AUGER Cyril et al. “Procyanidins and anthocyanidinsrich grape extracts prevent early atherosclerosisin hypercholesterol emichamsters” 1st International Conference of “Polyphenols and health”. Vichy 17-19 November (2003), France.
8. MANIJEH-SHAFIEE et al. “Grape and grape seed extract capacities at protecting LDL against oxidation generated by Cu2+, AAPH or SIN-1 and at decreasing superoxide THP-1 cell production. A comparison to other extracts or compounds.” Free Radical Research (2003) 37 (5), pp. 573-5845.
9. AUGER Cyril et al. “Phenolics from commercialized grape extracts prevent early atherosclerotic lesions in hamsters by mechanisms other than antioxidant effect.” Journal of Agricultural and Food Chemistry (2004), 52, 5297-5302.
and Treat Your Body with the World-best ® Antioxidants!
It Is Your Body! It Is Your Choice!
† These statements have not been evaluated by the US Food & Drug Administration.
FrenchGlory ® isotonic OPC antioxidants are nutritional supplements that help in fighting some nutritional deficient health problems due to imbalanced diet, not intended to diagnose, treat, care or prevent general diseases.
FrenchGlory ® is a registered trademark of AmeriNutra, Inc. It is a mark of a single word derived from 2 words - French Glory.